Department of Life Sciences

Department of Life Sciences

Odseka za nauku o zivim sistemima
  • Research
  • Researchers
  • Selected references
  • Current projects
  • Services
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Research at the Department has a fundamental and applied aspect:

  • Plant cell wall biophysics - a fundamental and applicable aspect of research, with the potential for application in assessing the quality of wood in the wood industry, or the quality of biomass of different origins.
  • Biomass from renewable sources for energy production and water purification - optimization of methods for isolating polymers and enzymes from waste biomass and their further use as a base in the synthesis of hydrogels for applications in industry and pharmacy.
  • Nanoparticles in the environment - interaction with plants, adoption and translocation of nanoparticles in plants, their possible toxicity, and their potential role in the modulation of certain types of stress.
  • Modification of antioxidant metabolism in stress - interaction of plants and environmental factors (abiotic and biotic) and mechanisms of acclimatization to changed conditions at different levels of organization of the plant organism.
  • Development of application of optical spectroscopy methods (fluorescent, infrared) in structural and diagnostic studies of plant and animal systems of different complexity.
  • Development of hyphenated analytical methods such as LC-MS and LC-PAD. Use of advanced mass spectroscopy and electrochemical methods in metabolite detection.
  • Research of health benefit components of food.
  • Redox biochemistry and biomedicine - redox and coordinative interactions of transition metals with biomolecules, drugs and pollutants; the role of transition metals and free radicals in human diseases.
  • Effects of low-dose ionizing radiation on unicellular algae as model organisms.
  • Fungal ecophysiology and biodiversity. Growth of plants and fungi, and defending against salt stress.
  • Development of application of mathematical and advanced statistical methods in the design of experiments and analyses of different experimental results.
  • Electrophysiological studies of physiological properties of cells of the nervous system, interactions of neurotransmitters and zinc, cerebrovascular processes and membrane properties of non - adhesive cells.
  • Investigations of the interaction of insects with natural and artificial agents for the purpose of different applications in agriculture.

Head of department: Dr Ksenija Radotić Hadži-Manić

  1. Živanović B.D. (2012) Surface tip-to-base Ca2+ and H+ ionic fluxes are involved in apical growth and graviperception of the Phycomyces stage I sporangiophore. Planta 236:1817-1829
  2. Živanović B.D. Shabala L.I., Elzenga T.J.M., Shabala S.N. (2015): Dissecting blue light signal transduction pathway in leaf epidermis using a pharmacological approach. Planta 242: 813-827
  3. Živanović, B.D., Ullrich K.K., Steffens B., Spasić S.Z., Galland P. (2018) The effect of auxin (indole-3-acetic acid) on the growth rate and tropism of the sporangiophore of Phycomyces blakesleeanus and identification of auxin-related genes. Protoplasma 255:1331–1347
  4. Fanrong Zeng, Sergey Shabala, Jelena Dragišić Maksimović, Vuk Maksimović, Edgar Bonales-Alatorre, Lana Shabala, Min Yu, Guoping Zhang, Branka D. Živanović (2018): Revealing mechanisms of salinity tissue tolerance in succulent halophytes: a case study for Carpobrotus rossi. Plant, Cell & Environment 41(11): 2654–2667
  5. Sedlarević Zorić, A., Morina, F., Toševski, I., Tosti, T., Jović, J., Krstić, O., & Veljović-Jovanović, S. (2019). Resource allocation in response to herbivory and gall formation in Linaria vulgaris. Plant Physiology and Biochemistry, 135, 224-232. (M21)
  6. Vojvodić S, Danilović Luković J, Zechmann B, Jevtović M, Bogdanović Pristov J, Stanić M, Lizzul A. M, Pittman K. J, Spasojević I. The effects of ionizing radiation on the structure and antioxidative and metal-binding capacity of the cell wall of microalga Chlorella sorokiniana. Chemosphere 260: 127553, 2020. DOI:10.1016/j.chemosphere.2020.127553
  7. Vojvodić S, Stanić M, Zechmann B, Dučić T, Žižić M, Dimitrijević M, Danilović Luković J, Milenković R. M, Pittman J. K, Spasojević I. Mechanisms of detoxification of high copper concentrations by the microalga Chlorella sorokiniana. Biochemical Journal 477: 3729 - 3741, 2020. DOI:
  8. Spasić S On 2D Generalization of Higuchi’s Fractal Dimension. Chaos, Solitions and Fractals, 2014, Vol. 69, December 2014, pp. 179-187. DOI:10.1016/j.chaos.2014.09.015
  9. Spasić S, 2010, Surrogate Data Test for Nonlinearity of the Rat Cerebellar Electrocorticogram in the Model of Brain Injury. Signal Processing. Vol.90, No. 12, pp. 3015-3025.
  10. Kesic S, Spasić S, Application of Higuchi’s fractal dimension from basic to clinical neurophysiology: A review, Computer Methods and Programs in Biomedicine, 2016, Vol. 133, pp. 55–70. DOI:10.1016/j.cmpb.2016.05.014
  11. Spasić S, Nikolić Lj, Mutavdžić D, Saponjic J. (2011) Independent complexity patterns in single neuron activity induced by static magnetic field. Computer methods and Programs in Biomedicine. Vol.104, Pp. 212-218.
  12. Spasić S, Ćulić M, Grbić G, Martać Lj, Sekulić S, Mutavdžić D, 2008, Spectral and fractal analysis of cerebellar activity after single and repeated brain injury. Bulletin of Mathematical Biology Vol. 70, No. 4, pp. 1235-1249.
  13. Spasić S, Kalauzi A, Ćulić M, Grbić G, Martać Lj (2005). Fractal analysis of rat brain activity after injury, Medical & Biological Engineering & Computing, Vol. 43, Issue 3, pp. 345-348.
  1. Radotić K., Dučić T., Mutavdžić D. 2000. Changes in peroxidase activity and isoenzymes in spruce needles after exposure to different concentrations of cadmium. Environmental and Experimental Botany 44: 105-113.
  2. Mitrović A., Donaldson L.A., Djikanović D., Bogdanović Pristov J., Simonović J., Mutavdžić D., Kalauzi A., Maksimović V., Nanayakkara B., Radotić K. 2015. Analysis of static bending-induced compression wood formation in juvenile Picea omorika (Pančić) Purkyne. Trees – Structure and Function 29: 1533-1543.
  3. Milenković I., Mitrović A., Algarra M., Lázaro-Martínez J. M., Rodríguez-Castellón E., Maksimović V., Spasić Z. S., Beškoski P. V., Radotić 2019. Interaction of carbohydrate coated cerium-oxide nanoparticles with wheat and pea: stress induction potential and effect on development, Plants, 8 478. doi: 10.3390/plants8110478
  4. Bartolić D, Maksimović V, Dragišić Maksimović J, Stanković M, Krstović S, Baošić R, Radotić K. 2020. Variations in polyamine conjugates in maize (Zea mays) seeds contaminated with aflatoxin B1: a dose–response relationship. Science of Food and Agriculture 100, 2905–2910.
  5. Stanković M, Bartolić D, Mutavdžić D, Marković S, Grubić S, Jovanović NM, Radotić K. 2021. Estimation of honey bee colony infection with Nosema ceranae and Varroa destructor using fluorescence spectroscopy in combination with differential scanning calorimetry of honey samples. Journal of Apicultural Research,
  6. Stanković M, Nikčević M, Radotić K. 2020. Annual variation of proteins and phenols in honey of a bee society using fluorescence spectroscopy: a way to assess effects of anti-varroa treatments on honey composition. European Food Research and Technology 246:1515–1518
  1. Jelušić, A., Berić, T., Mitrović, P., Dimkić, I., Stanković, S., Marjanović-Jeromela, A., Popović, T. 2021. New insights into the genetic diversity of Xanthomonas campestris pv. campestris isolates from winter oilseed rape in Serbia. Plant Pathology, 70(1), 35-49. doi: 10.1111/ppa.13273
  2. Živanović, B., Milić Komić, S., Tosti, T., Vidović, M., Prokić, L., & Veljović Jovanović, S. (2020). Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid-Mediated Drought Response in Tomato. Plants, 9(9), 1147.
  1. Marković, S., Stanković, S., Jelušić, A., Iličić, R., Kosovac, A., Poštić, D., & Popović, T. (2021). Occurrence and Identification of Pectobacterium carotovorum brasiliensis and Dickeya dianthicola Causing Blackleg in some Potato Fields in Serbia. Plant Disease, 105(4), 1080-1090.
  2. Opačić, M., Ristić, A.J., Savić, D., Šelih, V.S., Živin, M., Sokić, D., Raičević, S., Baščarević, V. and Spasojević, I. (2017). Metal maps of sclerotic hippocampi of patients with mesial temporal lobe epilepsy. Metallomics, 9(2), 141–148. DOI: 10.1039/c6mt00293e (Biochemistry & Molecular Biology 70/293, IF = 4.069, M21)
  3. Opačić, M., Stević, Z., Baščarević, V., Živić, M., Spasić, M. and Spasojević, I. (2018). Can oxidation-reduction potential of cerebrospinal fluid be a monitoring biomarker in amyotrophic lateral sclerosis? Antioxidants & Redox Signaling, 28(17), 1570–1575. DOI: 10.1089/ars.2017.7433 (Biochemistry & Molecular Biology 41/299, IF = 5.828, M21)
  4. Dragišić Maksimović, Jelena, Mojović, Miloš, Maksimović, Vuk, Römheld, Volker and Nikolic, Miroslav. 2012. Silicon ameliorates manganese toxicity in cucumber by decreasing hydroxyl radical accumulation in the leaf apoplast. Journal of Experimental Botany 63: 2411-2420. IF (2011): 5.364 Plant Sciences (11/190)
  5. Dragica Milosavljević, Dragosav Mutavdžić, Ksenija Radotić, Jasminka Milivojević, Vuk Maksimović, Jelena Dragišić Maksimović. 2020. Phenolic profiling of 12 strawberry cultivars using different spectroscopic methods. Journal of Agricultural and Food Chemistry. 68 (15): 4346-4354. IF (2019): 4.192 Agriculture, Multidisciplinary (4/58)
  6. Dragišić Maksimović, Jelena J., Živanović, Branka D., Maksimović, Vuk M., Mojović, Miloš D., Nikolic, Miroslav T. and Vučinić, Željko B. 2014. Filter strip as a method of choice for apoplastic fluid extraction from maize roots. Plant Science. 223: 49-58. IF (2013): 4.114 Plant Sciences (19/199)
  7. Simonović Radosavljević J, Bogdanović Pristov J, Mitrović A, Steinbach G, Mouille G, Tufegdžić S, Maksimović V, Mutavdžić D, Janošević D, Vuković M, Garab G, Radotic K (2017) Parenchyma cell wall structure in twining stem of Dioscorea balcanica. Cellulose 24 (11): 4653 – 4669.
  8. Šušić N., Bobinac M., Andrašev S., Šijačić-Nikolić M., Bauer-Živković A. (2019). Growth characteristics of one-year-old Hungarian oak seedlings (Quercus frainetto) in full light conditions. Šumarski list, 143(5-6), 221-229. (IF 2019 = 0.451)
  9. Korać Jačić J., Nikolić Lj., Stanković DM., Opačić M., Dimitrijević M., Savić D., Grgurić-Šipka S., Spasojević I., Bogdanović Pristov J. (2020) Ferrous iron binding to epinephrine promotes the oxidation of iron and impedes activation of adrenergic receptors. Free Radical Biology and Medicine, 148: 123-127. (Biochemistry & Molecular Biology 16/143, IF=6.170, M21)
  10. Korać J., Stanković DM., Stanić M., Bajuk-Bogdanović D., Žižić M., Bogdanović Pristov J., Grgurić-Šipka S., Popović-Bijelić A., Spasojević I. (2018) Coordinate and redox interactions of epinephrine with ferric and ferrous iron at physiological pH. Scientific Reports, 8: 3530. (Multidisciplinary Sciences 12/64, IF=4.122, M21)
  11. Milenković I., Algarra M., Alcoholado C., Cifuentes M., Lazaro-Martinez J. M., Rodriguez-Castellon E., Mutavdžić D., Radotić K., Bandosz T. J. (2019) Fingerprint imaging using N-doped carbon dots, Carbon, 144, 791-797. doi: 10.1016/j.carbon.2018.12.102
  12. Milenković I., Radotić K., Trifković J., Vujisić Lj., Beškoski P. V. (2021) Screening of semi-volatile compounds in plants treated with coated cerium oxide nanoparticles by comprehensive two-dimensional gas chromatography, Journal of Separation Science, 1-9. doi: 10.1002/jssc.202100145
  13. Milenković I., Borišev M., Zhou Y., Spasić Z. S., Leblanc R., Radotić K. (2021) Photosynthesis enhancement in maize via nontoxic orange carbon dots, Journal of Agricultural and Food Chemistry, 69 (19), 5446-5451. doi: 10.1021/acs.jafc.1c01094
  14. Dučić T., Milenković I., Mutavdžić D., Nikolić M., Martínez de Yuso M. V., Vučinić Ž., Algarra M., Radotić K. Estimation of carbon dots amelioration of copper toxicity in maize studied by synchrotron radiation-FTIR, Colloids and Surfaces B Biointerfaces, 204, 111828. doi: 10.1016/j.colsurfb.2021.111828
  15. Milenković I., Radotić K., Despotović J., Lončarević B., Lješević M., Spasić Z. S., Nikolić A., Beškoski P. V. (2021) Toxicity investigation of CeO2 nanoparticles coated with glucose and exopolysaccharides levan and pullulan on the bacterium Vibrio fischeri and aquatic organisms Daphnia magna and Danio rerio, Aquatic Toxicology, 236, 105867. doi: 10.1016/j.aquatox.2021.105867
  16. Cvetić Antić, T., Janošević, D., Maksimović, V.M., Živić, M., Budimir, S., Glamočlija, J., Mitrović, A.Lj. (2020) Biochemical and histological characterization of succulent plant Tacitus bellus response to Fusarium verticillioides infection in vitro. Journal of Plant Physiology, 244, 153086 (2018, Plant Sciences 55/228, IF 2.825) М21
  17. Dimitrijević MS, Bogdanović Pristov J, Žižić M, Stanković DM, Bajuk-Bogdanović D, Stanić M, Spasić S, Hagen W, Spasojević I. Biliverdin-copper complex at physiological pH. Dalton Transactions 2019;48:6061-6070
  18. Milić Komić S, Bogdanović Pristov J, Popović-Bijelić A, Zakrzewska J, Stanić M, Kalauzi A, Spasojević I. Photo-redox reactions of indole and ferric iron in water. Appl Catal B-Environ. 2016;185:174-180.
  19. Bragato, G., Fornasier, F., Bagi, I., Egli, S., & Marjanović, Ž. (2021) Soil parameters explain short-distance variation in production of Tuber aestivum in an oak plantation in the central-northern part of the Great Hungarian Plain (Jászság region, Hungary). Forest Ecology and Management, 479, 118578. (M21a) IF 2019-3.17
  20. Marjanović, Ž., Nawaz, A., Stevanović, K., Saljnikov, E., Maček, I., Oehl, F., & Wubet, T. (2020). Root-Associated Mycobiome Differentiate between Habitats Supporting Production of Different Truffle Species in Serbian Riparian Forests. Microorganisms, 8(9), 1331. (M21), IF2019- 4.152
  21. Marjanović, Ž, Glišić, A., Mutavdžić, D., Saljnikov, E., & Bragato, G. (2015) Ecosystems supporting Tuber magnatum Pico production in Serbia experience specific soil environment seasonality that may facilitate truffle lifecycle completion. Applied Soil Ecology, 95, 179-190. (M21) IF2016 =2.916
  • Horizon 2020, Innovation in Truffle cultivation, preservation, processing and wild truffle resources management (INTACT), 101007623
  • UNDP, LIQUID 3, 00094603/07/2020
  • European Commission, Oxygen sensing a novel mean for biology and technology of fruit quality, CA18210
  • European Commission, Data integration to maximise the power of omics for grapevine improvement, CA 17111
  • European Commission, European Soil-Biology Data Warehouse for Soil Protection” (EUdaphobase), CA18238,
  • Scientific and technological cooperation between the Republic of Serbia and the Republic of Croatia, Microstructure and mechanical characteristics of concrete with recycled materials
  • Innovation Fund/Proof of concept, Development of filters based on microalgae biomass for absorption of heavy metals from wastewater, 5033
  • Science Fund of the Republic of Serbia/PROMIS, Late embryogenesis abundant Proteins: Structural Characterization and Interaction with α-Synuclein (LEAPSyn-SCI), 6039663
  • The Innovation Fund/ Proof of Concept, Zinc encapsulated in biodegradable polymers: a sustainable solution for cereals boosting, 5262
  • Science Fund of the Republic of Serbia/PROMIS, Real -time detection and quantification of bioaerosols relevant for human and plant health (BREATHE), 6039613
  • Innovation Fund / Proof of Concept / Technology Transfer, Nanobionic stimulation of agricultural plants' productivity (NANOPLANT),  5419