University of Belgrade - Institute for Multidisciplinary Research

Dragica Spasojević

PhD in Biochemical sciences

Research Associate

Address: Bulevar despota Stefana 142, 11060 Belgrade

Telephone: (+381) 11 2078 451

Research area

Biopolymers in hydrogel synthesis and their application, plant enzymes-characterization, modifications and immobilizations.


Work on spectro- and microplate photometers, 2D chromatography equipments, advanced user of computer programs (MS Office packages, Origin, EndNote, etc.), fluent in English.

  • Biography
  • Projects
  • Selected publications

1.Work experience:

  • 2018-present: Research Fellow (Research Assistant Professor), Institute for Multidisciplinary Research, University of Belgrade.
  • 2012-2018: Research Assistant, Institute for Multidisciplinary Research, University of Belgrade.
  • 2011-2012: Research Trainee, Institute for Multidisciplinary Research, University of Belgrade.


  • 2017: PhD in Biochemistry, Faculty of Chemistry, Belgrade.
  • 2009: MSc in Biochemistry, Faculty of Chemistry, Belgrade.

3.Other professional activities

Courses taught:

  • May 2015, Proteomics School-Theoretical and practical foundations, Faculty of Chemistry, Belgrade.


  • Member of the Biochemical Society of Serbia.


  • 2011-Current: Study of structure-function relationships in the plant cell wall and modifications of the wall structure by enzyme engineering, national project funded by the Ministry of Education, Science and Technological Development of the Republic of
  • 2019-2021: Microstructural and mechanical characteristics of concrete with addition of renewable materials, bilateral project between the Republic of Serbia and the Republic of Croatia.


  • 2019-2020: Hydrogels with synthesized lignin oligomers as antimicrobial substances and wound healing agents – funded by the Technology Transfer Center of the University of Belgrade.
  1. Spasojević D., Prokopijević M., Prodanović O., Zelenović N., Polović N., Radotić K., Prodanović R. (2019) Peroxidase sensitive Tyramine carboxymethyl xylan Hydrogels for Enzyme Encapsulation. Macromolecular Research, 27,pp 764–771, doi: 1007/s13233-019-7111-7, IF = 2.047, M22.
  2. Stanković M., Bartolić D., Šikoparija B., Spasojević D., Mutavdžić D., Natić M., Radotić K. (2019) Estimation of variability of total content of proteins and phenols in honey using front face fluorescence spectroscopy coupled with MCR-ALS analysis. Journal of Applied Spectroscopy, 86, pp. 256-263, doi: 10.1007/s10812-019-00809-1, IF = 0.710, M23. – ID=1603
  3. Zmejkoski D., Spasojevic D., Orlovska I., Kozyrovska N., Sokovic M., Glamoclija J., Dmitrovic S., Matovic B., Tasic N., Maksimovic V., Sosnin M., Radotic K. (2018) Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. International Journal of Biological Macromolecules 118: 494-503, IF= 4.784, M21a.
  4. Prokopijević M., Prodanović O., Spasojević D., Kovačević G., Polović N., Radotić K., Prodanović R. (2017) Tyramine-modified pectins via periodate oxidation for soybean hull peroxidase induced hydrogel formation and immobilization. Applied Microbiology and Biotechnology 101: 2281-2290. (Biotechnology & Applied Microbiology 41/161, IF= 3.376, M21)– ID=1378
  5. Spasojević D., Zmejkoski D., Glamočlija J., Nikolić M., Soković M., Milošević V., Jarić I., Stojanović M., Marinković E., Barisan-Asenbauer T., Prodanović R., Jovanović M., Radotić K. (2016) Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. International Journal of Antimicrobial Agents 48: 732–735. (Microbiology 25/123, IF= 4.097, M21)– ID=1377
  6. Prodanovic O., Spasojevic D., Prokopijevic M., Radotic K., Markovic N., Blazic M., Prodanovic R. (2015) Tyramine modified alginates via periodate oxidation for peroxidase induced hydrogel formation and immobilization, Reactive and Functional Polymers, Vol. 93, p. 77–83. – ID=1180
  7. Tadić V., Petrić M., Milošević S., Cingel A., Raspor M., Spasojević D., Tadić J. (2014) Effect of phenol on germination capacity and polyphenol oxidase, peroxidase and catalase activities in lettuce. Archives of Biological Sciences, Vol. 66, No 4, p. 1503-1514. – ID=1179
  8. Prokopijević, Prodanović O., Spasojević D., Stojanović Ž., Radotić K., Prodanović R. (2013) Soybean hull peroxidase immobilization on macroporous glycidyl methacrylates with different surface characteristics. Bioprocess & Biosystems Engineering DOI 10.1007/s00449-013-1050-z. Engineering, Chemical 38/133, 1.869 – ID=886
  9. Spasojević D, Prokopijević M., Prodanović O., Pirtea G. M., Radotić K., Prodanovic R. (2013) Immobilization of chemically modified horse radish peroxidase within activated alginate beads, Hemijska Industrija, DOI 10.2298/HEMIND 1211 – ID=967
  10. Prodanović O., Prokopijević M., Spasojević D., Stojanović Ž., Radotić K., Knežević-Jugović Z., Prodanović R. (2012) Improved Covalent Immobilization of Horseradish Peroxidase on Macroporous Glycidyl Methacrylate-Based Copolymers. Applied Biochemistry and Biotechnology 168(5): 1288-1301 – ID=638