University of Belgrade - Institute for Multidisciplinary Research

Miloš Opačić

PhD in Biological Sciences

Research Associete

Address: Bulevar despota Stefana 142, 11060 Belgrade

Telephone: (+381) 11 2078 465

Research area

Molecular biology and biochemistry. Human neurological and neurodegenerative diseases. Metals metabolism. Oxidative stress.

Skills

  • Spatial biology and imaging: histology, 4i multiplexed imaging, in situ hybridization, enzyme activity histochemistry, bright field and fluorescent microscopy, laser microdissection microscopy
  • Computational and data analysis: image processing and analysis (ImageJ, histoCAT, Adobe), data processing and visualization (GraphPad Prism, IBM SPSS, MySQL Workbench), receptor-ligand analysis (CellphoneDB), network interactions and pathways (Cytoscape, Ingenuity Pathway Analysis)
  • Molecular and biochemical techniques: electrophoresis (SDS-PAGE, IEF), western blot, UV-Vis spectroscopy, oxidative stress biomarker assays
  • Biography
  • Projects
  • Selected publications

1. Work experience:

  • Postdoctoral Associate (2023 – 2024) @ Yale University, School of Medicine, New Haven, CT, USA
  • Research Associate (2022 – данас) @ University of Belgrade – Institute for Multidisciplinary Research, Belgrade, Serbia
  • Research Assistant (2018 – 2022), University of Belgrade – Institute for Multidisciplinary Research, Belgrade, Serbia
  • Research Trainee (2016 – 2018), University of Belgrade – Institute for Multidisciplinary Research, Belgrade, Serbia

2. Education:

  • Postdoctoral Training (2023 – 2024), Yale University, School of Medicine, New Haven, CT, USA
  • PhD in Biological Sciences (2015 – 2022), University of Belgrade – Faculty of Biology, Belgrade, Serbia
  • MSc in Molecular Biology and Physiology (2014 – 2015), University of Belgrade – Faculty of Biology, Belgrade, Serbia
  • BSc in Biology (2007 – 2014), University of Belgrade – Faculty of Biology, Belgrade, Serbia

 

3. Awards and certificates:

  • Young investigator travel award, ACTRIMS Forum 2024, West Palm Beach, FL, USA
  • Travel grant, European Network to Cure ALS (ENCALS) meeting 2018, Oxford, UK
  • Fellowship, Central European Exchange Program for University Studies (CEEPUS) 2017, Ljubljana, Slovenia
  • The best poster presentation at Serbian Biochemical Society’s 7th Conference: “Biochemistry of Control in Life and Technology” 2017, Belgrade, Serbia
  • Certificate of Proficiency in English (CPE) University of Cambridge, Cambridge English Language Assessment, 2012

4. Other professional activities

Memberships:

  • FENS and Serbian Neuroscience Society
  • FEBS and Serbian Biochemical Society
  • Serbian Biological Society

Current: 

  • 2025: Ministry of Science, Technological Development and Innovation of the Republic of Serbia (Contract No. 451-03-136/2025-03/200053)
  • 2022: COST Action CA21115: FeSImmChemNet URL: https://www.cost.eu/actions/CA21115/

Past:

  • 2017: Ministry of education, science and technological development of the Republic of Serbia: Bilateral cooperation project 06-00-118/2018-09/22 between Republic of Serbia, Institute for Multidisciplinary Research, University of Belgrade and Republic of Slovenia, Medical Faculty, University of Ljubljana and Republic of Slovenia, National Institute of Chemistry.
  • 2016: COST Action CA15133: FeSBioNet URL: https://www.cost.eu/actions/CA15133/
  • 2011: Ministry of education, science and technological development of the Republic of Serbia project number III43010
  1. Opacic M, Popovic B, Huang T, Henley M, Bhandarkar S, Pitt D. Mapping the functional interactome in MS lesions relevant to remyelination failure. ACTRIMS Forum 2024 – Abstract Sessions and Invited Sessions. Multiple Sclerosis Journal. 2024;30(1_suppl):3-17. https://doi.org/10.1177/13524585241252260
  2. Bogdanović I, Opačić M, Baščarević V, Raičević S, Ilić R, Grujičić D, Spasojević I, Ristić AJ. A potential role of mechano-gated potassium channels in meningioma-related seizures. Heliyon. 2023;9(10),e20761. https://doi.org/10.1016/j.heliyon.2023.e20761
  3. Opačić M, Ristic AJ, Sokic D, Baščarević V, Raicević S, Savić S, Zorović M, Zivin M, Selih VS, Spasojević I, Savić DZ. Regional distribution of cytochrome c oxidase activity and copper in sclerotic hippocampi of epilepsy patients. Brain Behav. 2021;11:e01986. https://doi.org/10.1002/brb3.1986
  4. Korać Jačić J, Nikolić LM, Stanković DM, Opačić M, Dimitrijević M, Savić DZ, Grguric-Sipka S, Spasojević I, Bogdanović Pristov J. Ferrous iron binding to epinephrine promotes the oxidation of iron and impedes activation of adrenergic receptors. Free Radical Biol Med. 2020;148:123–127. https://doi.org/10.1016/j.freeradbiomed.2020.01.001
  5. Opačić M, Zorović M, Savic D, Živin M, Raičević S, Bascarevic V, Ristic AJ, Sokic D, Spasojević I. Relationship between regional distributions of cytochrome c oxidase and copper-delivering chaperones in sclerotic hippocampi of epilepsy patients. in Book of Abstract: Federation of European Neuroscience Societies (FENS) Regional Meeting; 2019 Jul 10-13; Belgrade, Serbia.
  6. Opačić M, Stević ZD, Baščarević V, Zivić M, Spasić M, Spasojević I. Can oxidation- reduction potential of cerebrospinal fluid be a monitoring biomarker in amyotrophic lateral sclerosis? Antioxid Redox Signaling. 2018;28(17):1570–1575. https://doi.org/10.1089/ars.2017.7433
  7. Opačić M, Ristic AJ, Savić DZ, Selih VS, Zivin M, Sokic D, Raicević S, Baščarević V, Spasojević I. Metal maps of sclerotic hippocampi of patients with mesial temporal lobe epilepsy. Metallomics. 2017;9(2):141–148. https://doi.org/10.1039/C6MT00293E
  8. Bogdanović Pristov J, Opačić M, Dimitrijević M, Babic N, Spasojević I. A method for in-gel fluorescent visualization of proteins after native and sodium dodecyl sulfate polyacrylamide gel electrophoresis. Anal Biochem. 2015;480:6–10. https://doi.org/10.1016/j.ab.2015.04.006