University of Belgrade

Institute for
Multidisciplinary Research

Slađana Spasić

Dr Slađana Spasić

Research Professor

Department of Life Sciences (LS)

Phone: +381-11/2078-465


Curriculum vitae



2007: Ph.D. in Mathematics, Faculty of Mathematics, University of Belgrade. Ph.D. Thesis: \”Chaos Theory and Biosignal Fractal Analysis\”.


2003: M.Sc. in Artificial Intelligence, Center for Multidisciplinary Studies, University of Belgrade.


1991: B.Sc. in Mathematics, Department of Numerical Mathematics and Cybernetics, Faculty of Mathematics, University of Belgrade.


Work Experience


2018-present: Research Professor, Institute for Multidisciplinary Research, University of Belgrade.


2013-2018: Senior Research Fellow (Research Associate Professor), Institute for Multidisciplinary Research, University of Belgrade.


2008-2013: Research Fellow (Research Assistant Professor), Institute for Multidisciplinary Research, University of Belgrade.


2008-present: Assistant Professor for Mathematics and Statistics, Singidunum University, Belgrade.


1999-2008: Research Assistant, Center for Multidisciplinary Studies, University of Belgrade.


Research Interests


• Analysis and mathematical modeling of phisiological processes.

• Fractal analysis of time series.

• Nonlinear analysis of neuronal activity.

• Surrogate data testing.


Courses Taught


2009-present: \”Statistics for Engineers\” and \”Statistical methods\” (undergraduate courses), Singidunum University, Belgrade.


2008-present: \”Quantitative Methods in Science Research\”, Department for postgraduate and doctoral studies, Singidunum University, Belgrade.


Other Professional Activities


• Participation in international projects:


2007-2011: Serbian member of the WG1 COST Action BМ0601: Advanced Methods for the Estimation of Human Brain Activity and Connectivity (NEUROMATH).



• Professional membership in: Serbian Neuroscience Association and Biophysical Society of Serbia.


Representative publications



Vuković N., Spasić S. (2011) Statistika za inženjere. Singidunum University, Belgrade. ISBN: 978-86-7912-333-6. – ID=984

International book chapters


Ćulić M., Grbić G., Martać Lj., Kesić S., Todorović V., Spasić S., Sekulić S. (2006) Cerebellar responses to traumatic brain injury in rats. In: Neurobiology Today, Neurobiological Studies – From Genes to Behaviour, S. Ruzdijic and Lj. Rakic (Eds.), pp. 167-181. Research Signpost, Kerala, India. ISBN: 81-308-0107-8 – ID=828

Peer-reviewed international journals


Marinković V., Ranković-Janevski M., Spasić S., Nikolić-Kokić A., Lugonja N., Djurović D., Miletić S., Vrvić M.M., Spasojević I. (2016) Antioxidative activity of colostrum and human milk: Effects of pasteurization and storage. Journal of Pediatric Gastroenterology & Nutrition 62(6): 901-906. (Pediatrics 27/120, IF = 2.400, M21) – ID=1390


Kesić S., Spasić S. (2016) Application of Higuchi’s fractal dimension from basic to clinical neurophysiology: A review. Computer Methodsand Programs in Biomedicine 133:55-70. (Computer Science, Theory & Methods 16/105, IF = 1.862, M21)
– ID=1388


Spasic S., Kesic S., Stojadinovic G., Petkovic B., Todorovic D. (2015) Effects of the static and ELF magnetic fields on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe revealed by wavelet analysis, Comparative Biochemistry and Physiology, Part A 181: 27-35. – ID=1025


Subotić S., Višnjić-Jeftić Z., Spasić S., Hegediš A.,Krpo-Ćetković J., Lenhardt M. (2015) Concentrations of 18 elements in muscle, liver, gills, and gonads of sichel (Pelecuscultratus), ruffe (Gymnocephaluscernua), and European perch (Percafluviatilis) in the Danube River near Belgrade (Serbia). Water Air and Soil Pollution 226(9):287 (Environmental Sciences 124/225; IF = 1.551, M23)
– ID=1389


Spasic S.Z. (2014) On 2D generalization of Higuchi\’s fractal dimension, Solitons, Chaos and Fractals, 69: 179-187. – ID=1022


Kesic S., Nikolic LJ., Savic A.G., Petkovic B., Spasic S.Z. (2014) Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension, General Physiology and Biophysics, 33(3), 335-344. – ID=977


Djikanović V., Skorić S., Lenhardt M., Smederevac-Lalić M., Višnjić-Jeftić Z., Spasić S., Mićković B. (2014) Review of sterlet (Acipenser ruthenus L.1758) (Actinopterygii: Acipenseridae) feeding habits in the River Danube, 1694–852 river km. Journal of Natural History, DOI:10.1080/00222933.2013.877991. – ID=982


Kesić S, Nikolić Lj, Janać B, Spasić S (2014) Comparative Effect of 2.7mT and 10mT Static Magnetic Fields on the Snail Br Neuron Activity Using Fractal Dimension and ICA. Archives of Biological Sciences Vol. 66, No. 2, pp.563-572. – ID=1027


Djikanovic V, Skoric S, Lenhardt M, Smederevac-Lalic M, Visnjic-Jeftic Z, Spasic S, Mickovic B (2014) Review of starlet (Acipenser ruthnus L.1758) feeding habits in the Danube River, 1.694-852 river km. Journal of Natural History Vol. xx , No. x, pp. DOI:10.1080/00222933.2013.877991 – ID=1028


Jovanovic K.K., Savic A.G., Jankovic R., Radulovic S., Spasic S.Z., Radotic K. (2013) Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR. Medical Hypotheses 80: 376-379 – ID=666


Kalauzi A., Spasic S., Petrovic J., Ciric J., Saponjic J. (2012) Cortico-pontine theta carrier frequency phase shift across sleep/wake states following monoaminergic lesion in rat. General Physiology and Biophysics 31(2): 163-171 – ID=400


Spasic S., Kalauzi A., Kesic S., Obradovic M., Saponjic J. (2011) Surrogate data modeling the relationship between high frequency amplitudes and Higuchi fractal dimension of EEG signals in anesthetized rats. Journal of Theoretical Biology 289: 160-166. Biology 24/85, Mathematical & Computational Biology 11/47, 2.208 – ID=393


Spasić S., Nikolić Lj., Mutavdžić D., Saponjic J. (2011) Independent complexity patterns in single neuron activity induced by static magnetic field. Computer methods and Programs in Biomedicine 104: 212-218. Computer Science, Theory & Methods14/99, 1.516 – ID=535


Spasic S., Kesic S., Kalauzi A., Saponjic J. (2011) Different Anaesthesia in Rat Induces Distinct Inter-structure Brain Dynamic Detected by Higuchi Fractal Dimension. Fractals 19(1): 113-123 – ID=395


Spasić S., Nikolić Lj., Mutavdžić D. (2011) Effect of static magnetic field on fractal complexity of bursting activity of Br neuron in snail nervous system detected by factor analysis. Archives of Biological Sciences, Belgrade 63(1): 177-183 – ID=693


Spasić S., Perović A., Klonowski W., Djordjević Z., Duch W., Jovanović A. (2010) Forensics of features in the spectra of biological signals. International Journal of Bioelectromagnetism IJBEM – Special issue on Biosignal Applications and Modelling II 12(2): 62-75 – ID=690


Jovanović A., Perović A., Klonowski W., Duch W., Đorđević Z., Spasić S. (2010) Detection of structural features in biological signals. Journal of Signal Processing Systems 60(1): 115-129 – ID=691


Spasić S. (2010) Surrogate Data Test for Nonlinearity of the Rat Cerebellar Electrocorticogram in the Model of Brain Injury. Signal Processing 90(12): 3015-3025 – ID=692


Spasić S., Ćulić M., Grbić G., Martać Lj., Sekulić S., Mutavdžić D. (2008) Spectral and fractal analysis of cerebellar activity after single and repeated brain injury. Bulletin of Mathematical Biology 70( 4): 1235-1249 – ID=534


Grbić G., Ćulić M., Martać Lj., Soković M., Spasić S., Đoković D. (2008) Effect of camphor essential oil on rat cerebral cortical activity described by changes of fractal dimension. Archives of Biological Sciences, Belgrade 60(4): 547-553 – ID=689


Spasić S., Kalauzi A., Ćulić M., Grbić G., Martać Lj. (2005) Estimation of parameter kmax in fractal analysis of rat brain activity. Annals of the New York Academy of Sciences 1048: 427-429. Multidisciplinary Sciences 5/48 1.971 – ID=374


Kalauzi A., Spasić S., Ćulić M., Grbić G., Martać Lj. (2005) Consecutive differences as a method of signal fractal analysis. Fractals 13(4): 283-292 – ID=371


Spasić S., Kalauzi A., Grbić G., Martać Lj., Ćulić M. (2005) Fractal analysis of rat brain activity after injury. Medical & Biological Engineering & Computing 43(3): 345-348 – ID=372


Ćulić M., Martać-Blanuša Lj., Grbić G., Spasić S., Janković B., Kalauzi A. (2005) Spectral analysis of cerebellar activity after acute brain injury in anesthetized rats. Acta Neurobiologiae Experimentalis 65(1): 11-17 – ID=373


Kalauzi A., Spasić S. (2004) Estimation of neuronal population activity changes in rat cerebellum using one electrode. Comparative Biochemistry and Physiology – Part A 138: 61-68. Zoology 19/112, 1.635 – ID=370


Kalauzi A., Ćulić M., Martać Lj., Grbić G., Šaponjić J., Jovanović A., Janković B., Spasić S. (2003) New view on cerebellar cortical background activity in rat: simulation. Neuroscience Research Communications 32(3): 211-217 – ID=369


Ćulić M., Todorović V., Drndarević N., Nikolić A., Grbić G., Martać Lj., Kalauzi A., Spasić S. (2002) Age-related changes in the content of insulin-like growth factor-I in rat brain. Acta Veterinaria 52(5-6): 299-304 – ID=368


Current projects

Project ID
Project Title
Financial Source
My Status
OI173045 Fishes as water quality indicators in open waters of Serbia Ministry of Education, Science and Technological Development of the Republic of Serbia Member
Advanced analysis of micro scale images in biology and medicine Bilateral cooperation between the Republic of Serbia and the Republic of Belarus Member