University of Belgrade

Institute for
Multidisciplinary Research

Project information

Fate and effects of cytostatic pharmaceuticals in the environment and identification of biomarkers for an improved risk assessment on environmental exposure

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Project ID FP7 CytoThreat 265264
Project Title Fate and effects of cytostatic pharmaceuticals in the environment and identification of biomarkers for an improved risk assessment on environmental exposure

Project Leader Prof. Metka Filipič, National Institute of Biology, Ljubljana, Slovenia
IMSI Status Participates

Financial Source EU Framework Programme 7 (FP7)


Category of Project FP7 projects

 

PROJECT DESCRIPTION

The EC-FP7 funded project CytoThreat is emphasized on the evaluation of the environment and human health risks posed by cytostatic pharmaceuticals released into environment. We will use diverse chemical and biological techniques and advanced technologies to analyze the presence and distribution of selected cytostatics and their degradation products in the ecosystem and their adverse effects as single compounds and in mixtures to aquatic organisms and to human cell lines. Through the aim of developing new chemical analytical methods and studying formation of degradation products with concurrent application of whole range of toxicological tests including identification of early biomarkers for long term effects based on state of the art toxicogenomic approaches and bioinformatics the project has the potential to provide early diagnostic tools for predicting potential long term effects on ecosystems and human health. By achieving this we expect that CytoThreat results will provide new scientific knowledge and key data required in risk assessment procedures.

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PROJECT DURATION

 

From: 01.01.2011.   To: 31.12.2014.

 

PARTNERS

 

►National Institute of Biology, Slovenia

►Institute “Jozef Stefan”, Ljubljana, Slovenia

►Medical University of Vienna, Austria

►Szent Istvan University, Hungary

►The Second University of Naples, Italy

►Spanish Council for Scientific Research, Institute of Environmental Assessment and Water Research, Spain

►Institute for Medical Research and Occupational Health, Croatia

►SME RR&CO, Slovenia

 

PARTICIPANTS


No. Participant Institution
1.
Prof.dr Metka FilipičNational Institute of Biology, Slovenia
2.
Dr Zoran Gačić, research professorIMSI, University of Belgrade
3.
Dr Momir PaunovicInstitute for Biological Research "Siniša Stanković", University of Belgrade
4.
Prof. dr Branka VukovićFaculty of Biology, University of Belgrade
5.
Prof. dr Jelena Knezevic-VukcevicFaculty of Biology, University of Belgrade
6.
Dr Ester HeathInstitute “Jozef Stefan”, Ljubljana, Slovenia
7.
Prof. dr Siegfried KnasmuellMedical University of Vienna, Austria
8.
Prof.dr Ákos HorvathSzent Istvan University, Hungary
9.
Prof.dr Marina IsidoriThe Second University of Naples, Italy
10.
Dr Miren Lopez de AldaSpanish Council for Scientific Research, Institute of Environmental Assessment and Water Research, Spain
11.
Prof. dr Verica GarajInstitute for Medical Research and Occupational Health, Croatia
12.
Ilina HristovaSME RR&CO, Slovenia